• Fetal/Neonatal Alloimmune Thrombocytopenia: Pathogenesis, Diagnostics and Prevention 

      Brojer, Eva; Husebekk, Anne; Debska, Marzena; Uhrynowska, Malgorozata; Guz, Katarzyna; Orzinska, Agnieszka; Debski, Romuald; Maslanka, Krystyna (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-11-12)
      Fetal/neonatal alloimmune thrombocytopenia (FNAIT) is a relatively rare condition (1/1000–1/2000) that was granted orphan status by the European Medicines Agency in 2011. Clinical consequences of FNAIT, however, may be severe. A thrombocytopenic fetus or new-born is at risk of intracranial hemorrhage that may result in lifelong disability or death. Preventing such bleeding is thus vital and requires ...
    • What's with the boys? Lower birth weight in boys from HPA-1a alloimmunized pregnancies – New insights from a large prospective screening study in Poland 

      Coucheron, Tina; Uhrynowska, Malgorzata; Guz, Katarzyna; Orzińska, Agnieszka; Debska, Marzena; Gierszon, Agnieszka; Ahlen, Maria Therese; Bertelsen, eirin listau; Berge, gerd; Husebekk, Anne; Brojer, Ewa; Tiller, Heidi (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-07)
      Fetomaternal incompatibility in human platelet antigens (HPAs) can cause maternal alloimmunization, which in turn may lead to thrombocytopenia with or without intracranial hemorrhage (ICH) in the fetus or newborn. Retrospective studies suggest that boys from alloimmunized mothers may have higher risk of ICH and lower birth weight than girls. The objective of this study was to assess how maternal ...